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Value In Distinguishing Mesotheliomas From Other Tumors

Another interesting study is called, Value of the Ber-EP4 antibody in differentiating epithelial pleural mesothelioma from adenocarcinoma : The M.D. Anderson experience and a critical review of the literature - American Society of Clinical Pathologists, Chicago, IL, ETATS-UNIS (1931) (Revue) by ORDONEZ N. G. (1) ; 1998, vol. 109, no1, pp. 85-89 (21 ref.) Here is an excerpt: Abstract - Although most studies have indicated that Ber-EP4...more

Gemcitabine And Malignant Mesothelioma

Another interesting study is called, Expression is common in malignant Mesothelioma by G. KAFIRI, D.M. THOMAS, N.A. SHEPHERD, T. KRAUSZ, D.P. LANE, P.A. HALL Histopathology - Volume 21, Issue 4, pages 331334, October 1992. Here is an excerpt: The p53 tumour suppressor gene has been shown to be frequently mutated in a wide range of human neoplasms. This is accompanied by increased levels of p53 protein which become immunologically detectable in...more

Mesothelioma And Homozygous Deletion In Cell Lines

Another interesting study is called, Genetic alteration of the -catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3 p 21.3 homozygous deletion Oncogene 2001, vol. 20, no31, pp. 4249-4257 by Shigemitsu Kikuo; Sekido Yoshitaka ; Usami Noriyasu; Mori Shoichi; Sato Mitsuo; Horio Yoshitsugu; Hasegawa Yoshinori; Bader Scott A.; Gazdar Adi F. ; Minna John D.; Hida Toyoaki; Yoshioka Hiromu; Imaizumi Munehisa; Ueda Yuichi; Takahashi Masahide; Shimokata Kaoru Here is an excerpt: Abstract - The -catenin gene (CTNNB1) has been shown to be genetically mutated in various human malignancies. To determine whether the -catenin gene is responsible for oncogenesis in thoracic malignancies, we searched for the mutation in 166 lung cancers (90 primary tumors and 76 cell lines), one blastoma and 10 malignant mesotheliomas (two primary tumors and eight cell lines). Among the lung cancers, including 43 small cell lung cancers (SCLCs) and 123 non-small cell lung cancers (NSCLCs), we identified four alterations in exon 3, which is the target region of mutation for stabilizing -catenin. One primary adenocarcinoma had a somatic mutation from C to G, leading to...more

Suppressive Effects Of Mesothelioma Tumors

An interesting study is called, Dickkopf-1 antagonizes Wnt signaling independent of -catenin in human Mesothelioma - Biochemical and Biophysical Research Communications - Volume 323, Issue 4, 29 October 2004, Pages 1246-1250 by Amie Y. Lee, Biao He, Liang You, Zhidong Xu, Julien Mazieres, Noemi Reguart, Iwao Mikami, Sonny Batra and David M. Jablons...more

Immunohistochemical And Ultrastructural Features Of Mesothelioma

Another interesting study is called, Lymph Node Metastasis: as the Initial Manifestation of: Malignant Mesothelioma: Report of Six Cases by Sussman, Jeffrey M.D.; Rosai, Juan M.D. Here is an excerpt: Abstract - We present six cases in which lymphadenopathy was the initial manifestation of malignant mesothelioma. In five cases, the primary tumor...more

Mesothelioma And Therapy Induced Changes In Tumor Uptakes

An interesting study is called, Early Response Evaluation in Malignant Pleural Mesothelioma by Positron Emission Tomography With [18F] Fluorodeoxyglucose by Giovanni L. Ceresoli, Arturo Chiti, Paolo A. Zucali, Marcello Rodari, Romano F. Lutman, Silvia Salamina, Matteo Incarbone, Marco Alloisio, Armando Santoro - Journal of Clinical Oncology, Vol 24, No 28 (October 1), 2006: pp. 4587-4593 American Society of Clinical Oncology. Here is an excerpt: ABSTRACT - PURPOSE: Response evaluation with conventional criteria based on computed tomography (CT) is particularly challenging in malignant pleural mesothelioma (MPM) due to its diffuse pattern of growth. There is growing evidence that therapy-induced changes in tumor [18F]fluorodeoxyglucose (FDG) uptake as measured by positron emission tomography (PET) may predict response and patient outcome early in the course of treatment. PATIENTS AND METHODS: Patients with histologically proven MPM, not candidates to curative surgery, scheduled to undergo palliative chemotherapy with a pemetrexed-based regimen were eligible for this study. Patients were evaluated by FDG-PET and CT at baseline and after two cycles of therapy. A decrease of 25% or...more

Mesothelioma Cells And Resistance To Propylthiouracil

Another interesting study is called, The Human Type 2 Iodothyronine Deiodinase Is a Selenoprotein Highly Expressed in a Mesothelioma Cell Line by Cyntia Curcio, Munira M. A. Baqui, Domenico Salvatore, Bertrand H. Rihn, Steve Mohr, John W. Harney, P....more

The Value Of Thrombo Modulin As A Positive Marker For Mesothelioma

Another interesting study is called, Value of thrombomodulin immunostaining in the diagnosis of Mesothelioma by N.G. ORDEZ Histopathology Volume 31, Issue 1, pages 2530, July 1997. Here is an excerpt: Aims: Even with the benefit of...more

Simple Treatments For Oily Skin

Have you tried looking in the mirror only to see your shining face? Oily skin is a common problem worldwide. It is because of too much oil production by the sebaceous glands. The oil produced by these glands are necessary to keep your skin healthy....more

Imprinted Products For Metastatic Breast Cancer Awareness

Promotional products are oftentimes put to use as marketing tools by most products. But did you know that they can also be used as announcing instruments for charitable functions? Yes! These objects can be maximized as bequests for information drives...more

Basic Treatments For Piles

Your doctor is able to prescribe many treatments for the common complaint of piles, and there are also many that you are able to buy over-the-counter at your local pharmacy, but all these medications have one thing in common. They all treat the...more

Advanced Laser Vision Correction Treatment For Better Results

Advancements in medical science have led to the development of a range of surgeries to cure vision defects. Laser vision correction methods are the most popular among the contemporary eye surgeries. These methods utilize a special kind of laser...more
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