One interesting study is called, Translation of Microarray Data into Clinically Relevant Cancer Diagnostic Tests Using Gene Expression Ratios in Lung Cancer and Mesothelioma by Gavin J. Gordon, Roderick V. Jensen, Li-Li Hsiao, Steven R. Gullans, Joshua E. Blumenstock, Sridhar Ramaswamy, William G. Richards, David J. Sugarbaker, and Raphael Bueno - Cancer Res September 1, 2002 62. Here is an excerpt: Abstract - The pathological distinction...more
Another interesting study is called, The role of extrapleural pneumonectomy in malignant pleural mesothelioma. A Lung Cancer Study Group trial by VW Rusch, S Piantadosi and EC Holmes - Memorial Sloan-Kettering Cancer Center, New York, N.Y. The Journal of Thoracic and Cardiovascular Surgery, Vol 102, 1-9 Here is an excerpt: Malignant pleural mesothelioma is usually a fatal cancer for which operation has been the mainstay of treatment because...more
Another interesting study is called, Localized mesothelioma of the pleura: benign and malignant variants by N Okike, PE Bernatz and LB Woolner - The Journal of Thoracic and Cardiovascular Surgery, Vol 75, 363-372. Here is an excerpt: Mesothelioma, even of the pleura alone, is a ubiquitous pathological designation. The diffuse variety is associated with an ominous prognosis. The localized mesothelioma generally has been assumed to be benign. A review of tumors from 60 patients with localized pleural mesothelioma seems to justify separation into benign (52 patients) and malignant (eight patients) variants. Histologic criteria are used primarily to make this division. No single clinical feature allowed preoperative predictability concerning benignity or malignancy, although extrathoracic osteoarthropathy was seen only with benign lesions (20 percent), usually those greater than 7 cm. Follow-up periods of as long as 24 years revealed recurrent tumor in only two of the 58 patients with benign lesions and revealed a survival curve identical to that of the general population. All of the patients with the malignant variety had recurrence or metastasis, and all but one were dead within 2...more
Another interesting study is called, Modified RECIST criteria for assessment of response in malignant pleural Mesothelioma by M. J. Byrne and A. K. Nowak - Ann Oncol (2004) 15 (2): 257-260. Here is an excerpt: Abstract - Background: The growth pattern of malignant pleural mesothelioma makes the use of RECIST (response evaluation criteria in solid...more
Another interesting study is called, Mesothelioma: profile of keratin proteins and carcinoembryonic antigen: an immunoperoxidase study of 20 cases and comparison with pulmonary adenocarcinomas. - Am J Pathol. 1982 July; 108(1): 8087 by J. M. Corson and G. S. Pinkus. Here is an excerpt: Abstract - The distribution of keratin proteins and...more
Another interesting study is called, Value of the Mesothelium-Associated Antibodies Thrombomodulin, Cytokeratin 5/6, Calretinin, and CD44H in Distinguishing Epithelioid Pleural Mesothelioma from Adenocarcinoma Metastatic to the Pleura by P M Cury M.D., D N Butcher, C Fisher M.D., B Corrin M.D. and A G Nicholson D.M. - Mod Pathol 2000;13(2):107112. Here is an excerpt: Abstract - Until recently, the standard approach of most laboratories in distinguishing epithelioid pleural mesothelioma from metastatic adenocarcinoma has been a negative result from a panel of adeno-carcinoma-associated antibodies. However, several "mesothelium-associated" antibodies have been proposed as useful in this situation, and we have applied four of these putative mesothelioma markersthrombomodulin, cytokeratin 5/6, calretinin, and CD44Hto a series of 61 epithelioid pleural mesotheliomas and 63 metastatic adenocarcinomas with known primary sites (lung = 19; breast = 21; ovary = 6; colon = 10; kidney = 4; uterus, epididymis, pancreas = 1 case each). Of the mesotheliomas, 55 of 61 (90%) stained for thrombomodulin, 56 of 61 (92%) for cytokeratin 5/6, 47 of 51 cases (92%) were positive for calretinin, and 39 of...more
Another interesting study is called, Codeletion of p15 and p16 in primary malignant mesothelioma. By Xio S, Li D, Vijg J, Sugarbaker DJ, Corson JM, Fletcher JA. - Oncogene. 1995 Aug 3;11(3):511-5. Department of Pathology, Children's Hospital, Boston,...more
Another interesting study is called, Value of calretinin immunostaining in differentiating epithelial mesothelioma from lung adenocarcinoma. By Ordez NG. The University of Texas M.D. Anderson Cancer Center, Houston 77030 - Mod Pathol. 1998...more
Another interesting study is called, Neoadjuvant Chemotherapy Followed by Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma by Walter Weder, Peter Kestenholz, Christian Taverna, Stefan Bodis, Didier Lardinois, Monika Jerman, Rolf A. Stahel...more
An abdominal hernia occurs when either fatty tissue or an organ in the abdomen protrudes through a weak point or tear in the muscles or tissues around it. The protrusion can be labeled either as reducible, which means it can be pushed...more
American Cancer Treatment Organization is created in order to help people stay well or treat a persons problem. In majority of all cases people find themselves left alone and neglected by other individuals and the society as well. This is the main...more
Mobile phone deals are gaining popularity amongst the mobile lovers. These mobile phone deals have made it easier for the customer to get latest multifunctional handsets at pocket friendly rates. Previously it was a big problem for the...more