Another interesting study is called, Expression of c-sis (PDGF B-chain) and PDGF A-chain genes in ten human malignant mesothelioma cell lines derived from primary and metastatic tumors. By Versnel MA, Hagemeijer A, Bouts MJ, van der Kwast TH, Hoogsteden HC. - Department of Cell Biology, Immunology and Genetics, Erasmus University, Rotterdam, The Netherlands. Oncogene. 1988 Jun;2(6):601-5. Here is an excerpt: Abstract - Ten human malignant...more
Another interesting study is called, Randomized trial of doxorubicin versus cyclophosphamide in diffuse malignant pleural Mesothelioma by Srensen PG, Bach F, Bork E, Hansen HH - Cancer Treat Rep. 1985 Dec;69(12):1431-2. Here is an excerpt: Abstract - The effect of doxorubicin and cyclophosphamide in the treatment of diffuse, malignant pleural mesothelioma was evaluated in a randomized study. All patients were treated on an outpatient basis and...more
Another interesting study is called, The value of antibodies 44-3A6, SM3, HBME-1, and thrombomodulin in differentiating epithelial pleural mesothelioma from lung adenocarcinoma a comparative study with other commonly used antibodies by M. D. Anderson Cancer Center, University of Texas, Houston, Texas, ETATS-UNIS - 1997, vol. 21, no12, pp. 1399-1408 (73 ref.). Here is an excerpt: Abstract - The distinction between pleural mesothelioma and peripheral pulmonary adenocarcinoma involving the pleura continues to be a diagnostic problem in surgical pathology. In recent years, the use of various immunohistochemical markers to facilitate this differential diagnosis has become common. In this study, the value of monoclonal antibodies 44-3A6, SM3, HBME-I, and thrombomodulin is compared in the differentiation of these conditions. Fifteen (68.2%) of 22, and 10 (52.6%) of 19 mesotheliomas stained positively with 44-3A6 and SM3, respectively, whereas all 23 (100%) adenocarcinomas reacted with both antibodies. Sixteen (80%) of 20 mesotheliomas and 14 (63.6%) of 22 lung adenocarcinomas reacted with HBME-I, whereas 16 (80%) of 20 mesotheliomas and only three (11.1%) of 27 adenocarcinomas were...more
Another interesting study is called, Immunohistochemical Analysis of the p16INK4 Cyclin-Dependent Kinase Inhibitor in Malignant Mesothelioma - JNCI J Natl Cancer Inst (1995) 87 (24): 1870-1875 by Robert A. Kratzke, Gregory A. Otterson, Clint E. Lincoln, Stephen Ewing, Herbert Oie, Joseph Geradts and Frederic J. Kaye. Here is an excerpt: Abstract -...more
Another interesting study is called, Immunohistochemical staining for keratin and carcinoembryonic antigen in the diagnosis of malignant Mesothelioma by Holden, Janet M.D.; Churg, Andrew M.D. - American Journal of Surgical Pathology: April 1984 - Volume 8 - Issue 4. Here is an excerpt: Abstract - Using formalin-fixed, paraffin-embedded tissue and...more
An interesting study is called, Ultrastructural comparison of an adenomatoid tumor, lymphangioma, hemangioma, and Mesothelioma by Joseph B. Marcus MD,, Joseph A. Lynn MD, - Cancer Volume 25, Issue 1, pages 171175, January 1970. Here is an exerpt: Abstract - An electron microscopic study was made comparing an adenomatoid tumor with a hemangioma, lymphangioma, and 2 mesotheliomas in an attempt to elucidate the cell of origin of the adenomatoid tumor. Using ultrastructural criteria, one could say that neither the hemangioma or lymphangioma were structurally related to the adenomatoid tumor. It was not possible to morphologically distinguish between the cells of the mesothelioma and that of the adenomatoid tumor.Another interesting study is called, Phase II trial of high-dose cisplatin in patients with malignant mesothelioma. By Mintzer DM, Kelsen D, Frimmer D, Heelan R, Gralla R. - Cancer Treat Rep. 1985 Jun;69(6):711-2. Here is an excerpt: Abstract - Twenty-five patients with advanced malignant mesothelioma were treated in a phase II trial with high-dose cisplatin (DDP). All patients had measurable or evaluable disease. Seven patients had received prior chemotherapy. DDP (120...more
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Did you know that chronic neck pain, lumbar back pain, lumbar pain and sciatica pain are some of the most common chronic ailments in Canada? It is estimated by Statistics Canada that four out of five Canadians will suffer from one or...more