"Resident Evil Afterlife picks up where the third film ended
. Since the events of Resident Evil Extinction, Alice (Milla Jovovich) has been roaming the world searching for any remaining survivors. Alice also comes face to face with her arch-nemesis, Albert Wesker (Shawn Roberts), for the first time in the series. As she enters the ruined Los Angeles, she stumbles onto a base of Umbrella, surrounded by zombies. She then teams up with a group of survivors who had been hiding in Los Angeles since the T-virus outbreak, and helps them to free another group held-up in a prison, among them the brother of Claire (Ali Larter), Chris Redfield (Wentworth Miller)."