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What is it used for?
Duphaston treats conditions where there is a lack of the female hormone progesterone. It is used for:
* restoring bleeding in the absence of menstrual periods
* controlling irregular bleeding which is due to hormonal imbalance
* the treatment of endometriosis, which is a disease where fragments of the lining of the womb grow outside the womb in
the pelvic cavity
* painful periods which do not have any specific cause such as fibroids or infection
* a supplement for menopausal women who are taking hormone replacement therapy (HRT), in which it helps to protect the womb.
Contraindications and cautions:
Before taking any medicines, you should make sure that it is safe for you to do so.
Do not take Duphaston if you are allergic to any of the tablet. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
Do not take Duphaston if any of the following applies:
you have, or have had, or your doctor thinks you might have, breast cancer
you have had or your doctor thinks that you might have a tumour which is made worse by progestogens (e.g. meningioma)
you have, or you are being treated for, a blood clot in an artery or in a vein in your leg or anywhere else (a deep vein thrombosis), or a blood clot that has travelled to your lung or other parts of your body (an embolus), or you have had one of these conditions in the past
you have angina, or you have had a heart attack or stroke
you have or have had serious liver disease
you have or have recently had abnormal liver test results
your doctor told you that you have porphyria (an inherited metabolic disorder)
If you take Duphaston as part of a HRT treatment, you will also be prescribed an estrogen product. In addition to the above do not take Duphaston if any of the following applies:
you have had or your doctor thinks that you might have a tumour which is made worse by estrogen (e.g. endometrial cancer)
you have irregular or unusually heavy periods which have not been diagnosed or
you have or have had endometrial hyperplasia
For further information look at the leaflet in your estrogen pack or talk to your doctor or a pharmacist.
Side effects:
All medicines can have side effects. Often they are not serious but sometimes they can be. You may need medical treatment if you get some of the side effects.
Tell your doctor if you notice any of the following and they worry you:
* dizziness or headache
* breast pain or tenderness
* acne
* swelling of the ankles and feet
* weight change
* feeling sick
* change in body and facial hair. These are all mild side effects of Duphaston.
Tell your doctor immediately or go to Accident and Emergency at the nearest hospital, if you notice any of the following:
* menstrual changes, which may include change in the pattern, change in the cycle length, spotting, breakthrough bleeding, or no bleeding at all
* severe and/or sudden headache
* if you faint
* shortness of breath, slurred speech, or vision changes
* soreness of the veins particularly in the legs or groin
* heart or lung problems
* depression
* severe stomach pains
* yellowing of the skin or eyes (jaundice)
* skin rash, or irritation.
These are all serious side effects of Duphaston. You may need urgent medical attention.
Tell your doctor if you notice anything that is making you feel unwell.
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