DRUG CLASS AND MECHANISM: Combivent is a combination product consisting of two bronchodilators, albuterol (Proventil; Ventolin) and ipratropium (Atrovent) that is used in the treatment of chronic obstructive pulmonary disease (bronchitis and emphysema) when there is evidence of spasm (narrowing) of the airways. Bronchodilators dilate or enlarge the airways by relaxing the muscles surrounding the airways. Albuterol and ipratropium work by different mechanisms, but both cause the muscles of the airways to relax. (Ipratropium is an anticholinergic and albuterol is a sympathomimetic.)
GENERIC AVAILABLE: no
PRESCRIPTION: yes
PREPARATIONS: Combivent comes as a metered-dose aerosol inhaler delivering 90mcg of albuterol plus 18mcg of ipratropium per actuation of the inhaler.
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STORAGE: The inhaler should be stored at room temperature, 15-30C (59-86F) and kept away from moisture.
PRESCRIBED FOR: Combivent is used in the treatment of patients with chronic obstructive pulmonary diseases such as chronic bronchitis and emphysema when they are associated with bronchospasm or narrowing of the airways due to spasm of the muscles surrounding the airways.
DOSING: The dosing of Combivent must be individualized.
DRUG INTERACTIONS: No important drug interactions have been described with Combivent.
What Is Albuterol Sulfate?
Albuterol sulfate is a prescription medication used to treat airway spasms (called bronchospasms). Bronchospasms are most common in people with asthma, but can also occur in people with chronic obstructive pulmonary disease (COPD), which includes chronic bronchitis and emphysema. Some forms are also approved to prevent exercise-induced asthma.
Albuterol-containing products come as one of two different forms of albuterol: albuterol or albuterol sulfate. There is really no important difference between these two active ingredients. In fact, albuterol sulfate is often just shortened to "albuterol."
Albuterol Sulfate Products
Of the many different albuterol products, several of them contain albuterol sulfate. These products include:
Albuterol syrup
Albuterol tablets and long-acting tablets (VoSpire ER)
Albuterol solution products (for use in a nebulizer), including AccuNeb
Proventil HFA
Ventolin HFA
ProAir HFA.
Other products, such as the older albuterol inhalers (including Proventil or a generic albuterol inhaler) contain albuterol rather than albuterol sulfate.
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